The Fordyce Lab is awarded 2 Bio-X Seed Grants!

The Fordyce Lab has been awarded seed funding from Bio-X to support two projects in the lab!  

The first grant, "High-throughput Quantitative Enzymology: Developing and Deploying a Novel Microfluidic Platform", funds a collaborative project with Dan Herschlag's lab in the Department of Biochemistry that is being driven by Craig Markin, a joint postdoc between our labs.  The goal of this project is to develop a new microfluidic technology for producing and measuring Michaelis-Menten kinetics for thousands of rationally chosen enzyme mutants in parallel.  By making these measurements, we hope to learn more about how enzymes position active site residues for catalysis and improve efforts to design new enzymes.

The second grant, "Deciphering the Language of Cellular Protein Interaction Networks Using Spectrally Encoded Peptide-Bead Libraries", funds a collaborative project with Martha Cyert's lab in the Department of Biology that is being led by Huy Nguyen.  For this project, we are developing a new bead-based technology for studying how calcineurin, a human phosphatase that is the target of several immunosuppressant drugs, finds and binds its protein substrates in the cell.  With these measurements, we hope to improve prediction of calcineurin substrates and deepen our knowledge of cell signaling networks in vivo.

For more information on these projects (and to see the awesome science of the other funded grants!), check out the Bio-X website.

Welcome Huy Quoc Nguyen and congratulations!

Postdoctoral scholar Huy Quoc Nguyen has joined the Fordyce Lab! Huy graduated with a PhD in Chemistry from UC Davis and a BS from University of Washington. 

Huy was just awarded a ChEM-H seed grant with Christian Lentz from Matt Bogyo's lab to develop a new assay for protease specificity on spectrally encoded beads. Congratulations!

Welcome Rebecca, Varun, and Alex!

We have three new students in the Fordyce Lab for the summer! Rebecca Bromley-Dulfano is an undergraduate from the Physics department.  Alex Sockell is a rotation student with the Genetics Department. Varun Venkatesh is a high school student joining us as an intern.

Welcome!

 

Craig is awarded a CIHR Postdoctoral Fellowship!

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Craig Markin was awarded a Canadian Institutes of Health Research Postdoctoral Fellowship, which carries up to five years of full support! Read more about the fellowship here

Craig works jointly between our laboratory and the Herschlag laboratory to develop new microfluidic techniques for quantitatively measuring enzyme activity and catalysis across thousands of mutants in a single assay. 

Congratulations, Craig! 

Welcome Arjun Aditham and Scott Longwell!

Arjun and Scott have decided to join the lab as permanent members, and we are psyched!

Arjun graduated with a BS in Bioengineering from UC Berkeley, where he previously worked in Carolyn Bertozzi's lab using chemistry to explore microbiology.  He's now a graduate student in Bioengineering here at Stanford.

Scott graduated with a BA in Biochemistry and a minor in Computer Science from Bowdoin College, where he used bioorthogonal chemistry and mass spectrometry to study bacterial protein glycosylation.  After that, he worked at the Broad Institute in an analytical chemistry lab that supported drug discovery efforts.  Scott is also a graduate student in Bioengineering here.

Welcome Tyler Shimko!

Tyler Shimko has recently joined the Fordyce Lab as a permanent member! Tyler graduated with a BS in Biology from University of Utah in 2015 and is now a graduate student with the Department of Genetics.

Welcome, Tyler!

Bioengineering Retreat 2016!

Craig Markin gave a talk at the BioE retreat, and Adam, Kara, and Dan presented posters.  Adam and Kara's poster was awarded first prize - congratulations, Adam and Kara!

Welcome, Linfeng and Theo!

We are lucky to have Linfeng Yang and Theo Susanto rotating with us for the fall quarter from Bioengineering and Genetics, respectively.  Welcome, Linfeng and Theo!  In lab parlance, we are super jazzed and psyched to have you!

Congratulations to Kara on her seed grant!

Kara Brower and her team of fellow graduate students (Saara Khan, Masamitsu Kanada, Natalie Telis, and Evan Boyle) were just awarded a student-initiated seed grant from the Stanford Center for Systems Biology for developing a novel platform to study the epithelial/mesenchymal transition in metastasis.  You can read about the award here - congratulations, Kara!!!

Welcome Craig Markin!

We are also excited to welcome Craig Markin, the very first postdoctoral scholar in the lab!  Craig received his Ph.D. in Biochemistry from the University of Alberta for work done in the lab of Leo Spyracopoulos studying molecular mechanisms that drive ubiquitin signaling and DNA damage response.  He will be working as a joint postdoc between our lab and Dan Herschlag's lab to develop new high-throughput methods for quantitative measurement of enzyme kinetics.  Welcome, Craig!

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Welcome Chantal Guegler!

We are excited to welcome our new research associate, Chantal. Here she is pictured with her very first Fordyce Lab IDT order! Chantal recently graduated from UC Berkeley with a B.S. in Chemical Biology and plans to work on the MITOMI platform. Welcome to the group! 

Seeking applicants for joint postdoctoral position with Novartis and NIST/ABMS!

The Fordyce Lab at Stanford University is seeking applicants for a postdoctoral position working closely with NIST/ABMS and Novartis to develop and validate a new critical next-generation diagnostic test with direct implications for human health.  This unique position will include opportunities for close interaction with Novartis scientists, making it ideal for highly skilled and motivated recent PhD graduates interested in acquiring valuable industry-relevant experience.  Responsibilities will include both evaluating current methods of quantitative detection of RNA transcripts and developing new cutting-edge techniques for nucleic acid detection.  Experience with qRT-PCR, genome-wide sequencing, other quantitative molecular biology techniques, and/or novel assay development is required.  Experience with microfluidic device design and fabrication is a plus but is not required.  Interested applicants should send their CV and contact information for 3 references to: pfordyce at stanford dot edu.

Welcome to Naomi and Chris!

Naomi Genuth (from Biology) and Chris Probert (from Genetics) have decided to join us for their spring rotations.  Welcome, Naomi and Chris!